Former members

Dr.  H. Amaravadhi, PhD

PhD, Nanyang Technological University, Singapore






After Grüber's lab: Bate's Laboratory, Nanyang Technological University

Dr. Asha M. Balakrishna, PhD

PhD, National University of Singapore, Singapore






After Grüber's lab: Basak's Laboratory, NTU School of Biological Sciences

Dr. Sandip Basak

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Structural and mechanistic insight into the rotating subunit F of vacuolar ATPase



After Grüber's lab: Nanyang Assistant Professor at NTU School of Biological Sciences

Dr. Goran Biuković

PhD, University of Osnabrück, Germany 






After Grüber's lab: National University of Singapore, Singapore

Dr. Nebojša Bogdanović

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Characterization of the interactions of subunits α, ε and γ and functional insight into F-type ATP synthase of mycobacteria. Degree in 2019.



After Grüber's lab: The Southeastern Center of Microscopy of MacroMolecular Machines, University State University, United States of America

Dr. Chong Shi Min Sherilyn

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Enzymatic and structural insights into the mycobacterial alkylhydroperoxide reductase subunit C and repurposing of an antimalaria compound inhibiting the mycobacterial cytochrome bcc oxidase for tuberculosis disease. Degree in 2020


After Grüber's lab: Procter & Gamble, Singapore

Prof. Dr. Ünal Coskun


PhD Thesis:

Kopplungsmechanismus im A1-Komplex und 2- und 3D-Rekonstruktion der A-ATPase aus methanogenen Bakterien mittels Einzelpartikelanalyse von elektronenmikroskopischen Bildern. Degree in 2005



After Grüber's lab: Paul Langerhans Institute, Technical University Dresden, Germany

Dr. Phat Vinh Dip

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Structural and functional insights into subunit a of Saccharomyces cerevisiae V-ATPase and the Escherichia coli Alkyl Hydroperoxide Reductase complex



After Grüber's lab: Principal Scientist at Schrödinger Cambridge, United States of America

Asst. Prof. Shovanlal Gayen

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Functional and structural characterization of the stalk subunits F and H of the methanogenic A1AO ATP synthase. Degree in 2010



After Grüber's lab: Dr. Harisingh Gour Central University, Department of Pharm. Sciences, Sagar, India

Dr. Adam Hotra

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Modeling studies for tuberculosis enzyme inhibitor. Degree in 2018


After Grüber's lab: Novo Nordisk, Slovakia

Dr. Cornelia Hunke

PhD, University of Braunschweig, Germany


PhD Thesis:

Synthetische Mimetika der Bindungsstelle der Mena-EVH1-Domäne für prolinreiche Liganden: Design, Synthese und Untersuchung des Bindungsverhaltens. Degree in 2005

Dr. Neelagandan Kamariah

PhD, Centre of Advanced Study in Crystallography and Biophysics, University of Madras, India



After Grüber's lab: Institute for Stem Cell Science and Regenerative Medicine, Bangalore, India

Dr. Anil Kumar

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

The trail of nucleotides and the traits of ADP/ATP-binding inside the subunits A and B of the archaeal energy producer A1AO ATP synthase. Degree in 2010



After Grüber's lab: ImmunOs Therapeutics AG, Schlieren, Switzerland

Dr. Arvind Kumar

PhD, Nanyang Technological University, Singapore

PhD Thesis: 

Structural and mechanistic insights into Mycothiol disulfide reductase, Mycoredoxin-1 and peroxiredoxin alkyl hydroperoxide subunit E of Mycobacterium tuberculosis. Degree in 2017


After Grüber's lab: Thermo Fisher Scientific, United States of America

Dr. Chitra Latka

PhD, CSIR-IGIB, New Delhi, India






After Grüber's lab: Nanyang Technological University, Singapore

Dr. Lim Jack Wee

PhD, National University of Singapore, Singapore


PhD Thesis: 

Understanding protein structure-function relationship by NMR spectroscopy.


After Grüber's lab: A*STAR - Agency for Science, Technology and Research

Dr. Wilson Nartey

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Mechanistic insights into Escherichia coli Alkyl Hydroperoxide Reductase complex formation. Degree in 2016



After Grüber's lab: Arnie Charbonneau Cancer Institute, University of Calgary, Canada

Dr. Ankita Pan

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Structure and functional characterization of flavivirus non-structural protein 3 (NS3) in solution and atomic and enzymatic insights of vancomycin resistant Enterococcus faecalis (V583) alkyl hydroperoxide subunit C. Degree in 2018


After Grüber's lab: A*STAR - Agency for Science, Technology and Research 

Dr. S. Rishikesan

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Solution structure of the stalk subunits E and G of the vacuolar ATPase from yeast and interaction studies of subunits E and G with the neighboring subunits. Degree in 2011

Dr. Vincenzo Rizzo

MD, PhD


PhD Thesis: 

Characterization of subunit E of the V-ATPase. Degree in 2004



After Grüber's lab: Pirmasens Hospital, Germany

Dr. Saw Wuan Geok

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Solution studies on the Dengue virus Non-structural protein 5 and -3 as well as the Capsid protein. Degree in 2017



After Grüber's lab: NTU Institute of Structural Biology, Singapore

Dr. Shin Joon

PhD






Dr. Hendrik Sielaff

PhD, University of Osnabrück, Germany






After Grüber's lab: National University of Singapore, Singapore

Dr. Bharti Singal

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Structural and mechanistic insights into the Rel protein of Mycobacterium tuberculosis. Degree in 2020



After Grüber's lab: Standford University, United States of America

Dr. Dhirendra Singh

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Unravalling structural and mechanistic elements of catalytic subunits A and coupling subunit F and structural and kinetic studies of the A3B3D and A3B3DF-subcomplexes of the Methanosarcina mazei Gö1 provide insights into the single molecule dynamics of this engine. Degree in 2017


After Grüber's lab: Thermo Fisher Scientific, Netherlands

Dr. Lavanya Sundararaman

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

The role of N157 of A-ATP synthase subunit B in nucleotide binding and expression, production and structural and mechanistic features of subunits α and ε of Mycobacterium tuberculosis F-ATP synthase. Degree in 2016

Dr. Vikramjeet Singh Tadwal

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Crystallographic details of the nucleotide-binding pocket of subunit A and B of A-ATP synthases and insight into the nucleotide-binding subunit α of the Escherichia coli F-ATP synthase. Degree in 2011


After Grüber's lab: Singapore Immunology Network (SIgN), Singapore

Dr. Youg Raj Thaker

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Caspase interaction of antiapoptotic Livin as well as the vacuolar ATPase (V- ATPase) and structural insight into the subunits a and d of the yeast V-ATPase. Degree in 2009


After Grüber's lab: Sharpe Laboratory, Harvard Medical School, Department of Microbiology and Immunology, Boston, United States of America

Dr. Giancarlo Tria

PhD, University of Hamburg, Germany






After Grüber's lab: Maastricht University, Netherlands

Dr. C.F. Wong

PhD, Nanyang Technological University, Singapore


PhD Thesis: 

Structure and Regulation of the Mycobacterial F1-ATPase. Degree in 2022


After Grüber's lab: Centre for Discovery and Innovation, Hackensack Meridian Health, United States of America

Claudia Karin Beushausen

M.S Eng






Logeshwari MN

M. Tech (Biotechnology) 





After Grüber's lab: Nanyang Technological University, Singapore


Sek Mun Foong

M.Sc., Nanyang Technological University, Singapore


Master Thesis:

Mechanistic insights into Escherichia coli Alkyl hydroperoxide subunit C (AhpC) and the molecular switch for peroxide robustness. Degree in 2016


After Grüber's lab: Innowave Tech Pte Ltd, Singapore

Christina Hohn

Dipl. Biol., Saarland University, Germany


Diploma Thesis:

Functional and structural studies on the A3B3DF-subkomplexes of the A-ATP synthase from M. mazei Gö1. Degree in 2005


Sandra Juliano

Dipl. Biol., Saarland University, Germany


Diploma Thesis:

Characterization of stalk subunit C from S. cerevisiae. Degree in 2004

Ingmar Schäfer

Dipl. Biol., Nanyang Technological University, Singapore and Saarland University, Germany 


Diploma Thesis:

High resolution crystal structure of the nucleotide-binding subunit B and its coupling with subunit F of the motor protein A1AO ATP synthase from Methanosarcina mazei Gö1. Degree in 2006


After Grüber's lab: MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

Faridah Banu D/O Rafiuddin

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Purification and characterization of Mycobacterium tuberculosis mycothiol reducatase and generation of its functional domains. Degree in 2016

Chionh Boon Bin

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

A critical a-helical elements of the N-terminal domain of the Alkylhydroperoxide Reductase subunit F (AhpF) of Enterococcus faecalies, an essential enzyme in H2O2 reduction. Degree in 2016


After Grüber's lab: Hoya Technosurgical, Singapore

Kerk Hwee Wen

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Targeting Mycobacterium abscessus bioenergetics: Mutational studies of F1-ATPase subunits α and ε to shed light on to their role in latent ATPase hydrolysis. Degree in 2022


After Grüber's lab: Medisix Therapeutics, Singapore

Jes Kwek Hui Min

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Degree in 2022


After Grüber's lab: PhD Student in Nanyang Technological University, Singapore

Lau Aik Meng

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Characterizing subunit e of the Mycobacterial F-ATP synthase. Degree in 2018

Leow Chen Yen

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Developing expression and purification methods for the Mycobacterium abscessus and M. smegmatis F1 (δαβγε)-ATPase and characterization of their enzymatic activity. Degree in 2023


After Grüber's lab: Pursuing Masters in University of Cambridge, England

Li Ying

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Biophysical approaches to study the structural alterations in subunit C and the localization of its stalk partner d inside the yeast vacuolar ATPase. Degree in 2007

Li Weixiang Daphne

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Characterization of a Plasmodium falciparum multi-drug resistance protein.

Qin Yi Xi

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Expression and purification of subunit B of the V1VO ATPase from Aedes albopictus. Degree in 2009

Wu Yulei

B. Sc (Hons); Nanyang Technological University, Singapore


Final Year Project Thesis:

Cloning, expression, purification and biochemical characterization of subunit E and the truncated forms of its neighboring subunit H of the A1AO ATP synthase from Methanocaldococcus jannaschii. Degree in 2007


After Grüber's lab: Maybank, Singapore

Lewis Zeng Zhengjie

B. Sc (Hons); Nanyang Technological University, Singapore and Saarland University, Germany 


Final Year Project Thesis:

Expression, purification and structural characterization of the non-homologous region of subunit A of the A1AO ATP synthase. Degree in 2008

Andrea Armbrüster

Medical Technical Assistant, Universität des Saarlandes Klinikum, Homburg, Germany





After Grüber's lab: Universität des Saarlandes Klinikum, Homburg, Germany

Jubi Bhaskara Kurup

Project Officer, Nanyang Technological University, Singapore





V. P. Hema Priya

Project Officer, Nanyang Technological University, Singapore